Treating Androgenetic Alopecia in Women

Androgenetic alopecia, commonly known as female pattern hair loss, is a widespread issue that affects millions of women worldwide. While traditionally associated with men, hair loss in women is becoming increasingly recognized and addressed in medical circles. In a recent discussion between two esteemed hair surgeons, Dr. Sam Lam and Dr. Shadi Zari, insights were shared on how they approach this condition in their respective practices, highlighting the nuances of treatment strategies and the importance of personalized care.

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Prevalence of Female Hair Loss

Female hair loss, particularly androgenetic alopecia, is more common than many might think. Dr. Shadi Zari, an American board-certified dermatologist practicing in Saudi Arabia, shared that a significant portion of his patient base consists of women suffering from hair loss. Approximately 70% of those who seek consultation are female, a stark contrast to the traditionally male-dominated field of hair restoration. However, despite this high percentage, only about 5-10% of these women proceed with hair transplantation. This statistic underscores the complexity of female hair loss and the importance of thorough evaluation before opting for surgical intervention.

Dr. Sam Lam, a Dallas-based hair surgeon, noted that around 50% of his consultation patients are women, but only about 25% of those women qualify for hair transplantation. Overall, Dr. Lam performs hair transplants on 70% of men and 30% of women. This is quite unique in the field, where most practices are heavily skewed towards male patients. Both doctors agree that understanding the underlying causes and the extent of hair loss is crucial before determining the best course of action.

Medications for Female Hair Loss

When it comes to treating female hair loss, the approach can vary significantly based on the patient’s circumstances. Dr. Zari starts with topical Minoxidil, the only FDA-approved medication for genetic hair loss in women. However, he quickly pointed out that most treatments used are off-label, meaning they aren’t specifically approved for this use by regulatory bodies. The choice of treatment often depends on whether the woman is planning to become pregnant, as many medications can have adverse effects on pregnancy.

For women in their childbearing years, Dr. Zari prefers non-invasive options like PRP (Platelet-Rich Plasma) and autologous micrografting. These treatments involve using the patient’s own blood or tissue to stimulate hair growth, making them a safer option for those looking to avoid synthetic drugs. However, if pregnancy is not a concern, he might opt for Oral Minoxidil or DHT blockers, which can be more effective but come with a higher risk of side effects.

Dr. Lam, on the other hand, has shifted away from traditional biochemical therapies due to their potential side effects, particularly for women of childbearing age. Instead, he has embraced natural therapies, which he believes offer a safer and often more effective solution. One of his key treatments involves plant-based growth factors delivered through specialized devices that do not require needles. He has also developed a product called Folly Flow, which he uses to manage hair shedding, particularly after surgery.

Treating Hormonal Hair Loss 

One of the most challenging aspects of treating female hair loss is managing the hormonal imbalances that often accompany it. Dr. Lam noted that he frequently encounters women whose hair loss has accelerated due to hormone therapy, particularly testosterone, which is sometimes prescribed post-menopause to enhance sex drive. This hormone can exacerbate hair loss, particularly in the frontal and temporal regions of the scalp.

In such cases, Dr. Lam may recommend biomedical therapies like Finasteride, a drug that blocks DHT, the hormone responsible for hair loss in many cases. However, he is cautious about prescribing this to women of childbearing age due to the potential risks. Instead, he leans towards natural treatments and only resorts to biomedical therapies when absolutely necessary.

Dr. Zari uses a lower dose of oral minoxidil for his female patients at 0.625 milligrams and gradually increases it, with the maximum dosage he uses being 1.25 milligrams. He emphasized the need to start with a lower dose to minimize side effects, particularly unwanted body hair growth, which can occur at higher doses. On the other hand, Dr. Lam tends to start his patients on a slightly higher dose of 2.5 milligrams. He acknowledged that while this higher dose can be more convenient and potent, it still only offers about a 15% chance of hair regrowth. 

Hair Transplantation: When and How?

Hair transplantation is a common treatment for male pattern baldness, but its application in women is more complicated. Both doctors agree that surgery should be considered only after other treatments have been exhausted, and even then, it may not be suitable for all women.

Dr. Zari highlighted a study he conducted involving 1,000 female patients, which revealed that those with thinning hair in the donor area (typically at the back of the scalp) are less suitable candidates for hair transplantation. This finding underscores the need for careful evaluation and often a more conservative approach when treating women’s hair loss.

Dr. Zari prefers FUE (Follicular Unit Extraction) for most of his female patients. This method allows for the selection of the healthiest hair follicles, which is particularly important for women with limited donor hair. FUE is less invasive than FUT (Follicular Unit Transplantation), which involves removing a strip of scalp from the donor area. However, Dr. Zari does use FUT for larger sessions, where more hair follicles are needed.

Dr. Lam, on the other hand, primarily uses FUT for his female patients. He believes this method offers several advantages, particularly in preserving the visual density of the donor area. Women are often more concerned about the appearance of their donor area than men, and FUT allows Dr. Lam to harvest hair without significantly reducing the density of the surrounding hair. He has also developed a technique to minimize post-operative pain, which involves using Botox to numb specific nerves in the scalp.

Dr. Sam Lam discussed the pattern of hair loss in females, specifically focusing on what he refers to as the “TL reverse L” or “dumbbell” pattern. This pattern typically involves a central forelock area at the front of the scalp, which may taper back into the part line, creating an L-shaped or reverse L-shaped area of thinning. He also noted that women often maintain hair density in the crown but experience a volume deficit, making them self-conscious about thinning in these key areas.

In performing hair transplantation for this pattern, Dr. Lam focuses on strategically placing grafts in the most visibly affected areas, particularly the frontal area and the part line. He may also add grafts in a smaller circle at the crown to create lift and fullness without needing extensive coverage. Dr. Lam’s approach is to prioritize these critical areas to provide women with a significant improvement in volume and shape, often with just one session while managing expectations that a second session may be needed to achieve desired results.

Managing Post-Surgical Recovery

One of the biggest concerns for women undergoing hair transplantation is the recovery process, particularly the risk of post-operative shedding, known as telogen effluvium. This condition can cause significant hair loss in the months following surgery, which can be devastating for patients who are already struggling with hair loss.

To mitigate this, Dr. Lam uses his Folly Flow product to stabilize the scalp and reduce shedding. He has also developed a pain management technique that involves injecting small amounts of Botox into specific points on the scalp. This method has been highly effective in reducing post-operative pain, with many of his patients reporting little to no discomfort after surgery.

Personalized Treatment for Hair Loss

Both Dr. Lam and Dr. Zari agree that there is no one-size-fits-all solution to female hair loss. Each patient’s situation is unique, and treatment plans must be tailored to their specific needs and circumstances. While they have different approaches, both doctors have had great success in their practices and have helped many women regain their confidence through effective hair loss treatments.

Conclusion

In conclusion, the key to successful treatment of female hair loss lies in a personalized approach that takes into account the individual’s medical history, hormonal profile, and personal preferences. With the right combination of medical and surgical treatments, it’s possible to achieve significant improvements in hair density and appearance, helping women regain their self-esteem and quality of life.

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