ISHRS 2023 CME Webinar September 27 – The Good Hair: Non-Pharmaceutical Supplements and Products Used to Treat Hair Thinning. What is the Evidence to Support Them?

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ISHRS 2023 CME Webinar

The Good Hair: Non-Pharmaceutical Supplements and Products Used to Treat Hair Thinning. What is the Evidence to Support Them?

Wednesday, September 27, 2023
12:00 PM Central Time/Chicago
(Time Zone Conversion)
Duration: 2 hours

Available On Demand – Register below to view the recording

Registration Fees Per Webinar

Physician Attendee of ISHRS 2022 Panama World Congress$0.00 USD
ISHRS Physician Member
Non-Attendee of ISHRS 2022 Panama World Congress
$75.00 USD
ISHRS Physician Pending-Member
Non-Attendee of ISHRS 2022 Panama World Congress
$100.00 USD
Physician Non-Member
Non-Attendee of ISHRS 2022 Panama World Congress
$125.00 USD
ishrs cme 2023 september


Moderator: Sharon Keene, MD, FISHRS | USA
Co-Moderator: Bruno Ferreira, MD
| Portugal

Program Description

The live online webinar will occur on the date and time as noted. The live program will be recorded and available for viewing on demand until January 10, 2024. This 2-hour CME activity is a live webinar which will be recorded with the intention to be re-watched or viewed as on-demand education.

This webinar is being conducted to inform medical practitioners on a range of supplements that patients may consume in an effort to treat hair thinning and hair loss. Some of the supplements being covered should only be used in certain circumstances or with established nutritional deficiencies, others may have intrinsic properties that can promote hair growth, while others have little or no ability to promote hair growth despite being frequently touted to do so and may have other detrimental effects when improperly used.

Finally, the webinar seeks to educate medical practitioners about the popularity of, types of, and indications for testosterone supplements as well as their role in AGA hair loss and how to treat it. The webinar will conclude with a lecture on naturally occurring 5 alpha reductase inhibitors and the evidence for and limits of efficacy, for patients who are opposed to pharmaceutical intervention. The online live component will include presentations, panel discussion, and audience participation via verbal questions and discussion, typing chat Q&A and polling.

Professional Practice Gap

Exploring the roles hormonal, nutritional and non-pharmaceutical supplements have on hair growth and hair loss, both positive and negative as well as identifying supplements that have been touted but don’t have a significant role in treating hair loss in order to properly counsel patients on supplement use, and effective hair loss treatments.

Educational Need

Medical science and thus clinical recommendations are often changed by updated research and clinical scenarios.  A review of the most recent published medical literature on this topic will be presented to update and inform hair restoration specialists in order to properly educate patients about supplement use and the effect on hair thinning.

Learning Objectives

As a result of participating in this webinar, the attendees should be able to:

  • Name some of the most common nutritional deficiencies that contribute to hair loss and how to identify and treat them.
  • Be familiar with some of the most common commercial supplements that patients are using or asking about to treat hair shedding or to promote hair growth; the strength of supporting data or lack thereof for various non-pharmaceutical supplements; and when patients should be counseled against their routine use 
  • Discuss why commonly used hormonal supplements (Testosterone) are popular and often prescribed despite their negative impact on hair growth in genetically predisposed patients, and how to treat hair loss when it occurs.
  • Be aware of non pharmaceutical natural 5 ARI’s or the hormone melatonin as hair growth promoters, and the strength and weakness of evidence to support them.

Target Audience and Prerequisites

This webinar is taught at the physician level. It is open to all levels and geared toward advanced hair restoration surgeons.


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    D., Cells 10(11):2957 October 2021
  2. Neuroendocrinology of the hair follicle: principles and clinical perspectives, Paus, R., Langan, et
    al, Trends in Molecular medicine, Volume 20, issue 10, Oct 2014, pg 559-570
  3. Human skin: an independent peripheral endocrine organ, Zouboulis, C. Et al Feb 2020,
    Hormone research, 54(5-6), 230-243,
  4. Melatonin and Health: Insights of Melatonin Áction, Biological Functions, and Associated
    Disorders, Ahmad, S, Ali, A, et al Cellular and Molecular Neurobiology, Feb 8, 2023
  5. Quality Certification Programs for Dietary Supplements, Akabas S. , Vannice, G., Atwater J. et al
    Journal of the Academy of Nutrition and Dietetics, 2016, 1370-1379
  6. Karashima T, Tsuruta D, Hamada T, Ono F, Ishii N, Abe T, Ohyama B, Nakama T, Dainichi T,
    Hashimoto T. Oral zinc therapy for zinc deficiency-related telogen effluvium. Dermatol Ther.
  7. Malanin K, Telegdy E, Qazaq H. Hair loss and serum zinc values among Arab females in Al Ain
    region, United Arab Emirates. Eur J Derm. 2007;17:446-7. 
  8. Pang, Q., Qi, X., Jiang, Y. et al. Clinical and genetic findings in a Chinese family with VDR-
    associated hereditary vitamin D-resistant rickets. Bone Res 4, 16018 (2016). 
  9. Malloy, P.J., Feldman, D., The role of Vitamin D receptor mutations in alopecia,  Mol Cell
    Endocrinol, Vol 347, pp 90-96 Dec 2011
  10. Medeiros, J.F.P. et al. The impact of vitamin D supplementation on VDR gene expression and
    body composition in monozygotic twins: randomized        controlled trial. Sci Rep 10, 11943
  11. Hoot,  J, Sadeghpour, M. et al,  Nonscarring Alopecia Associated With Vitamin D
    Deficiency , Cutis. 2018 July;102(1):53-55  ( Dept of Dermatology, University of Pittsburgh,
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  12. Nair,  R.,   Maseeh, A.,   Vitamin D: The “sunshine” vitamin, J Pharmacol
    Pharmacother. 2012 Apr-Jun; 3(2): 118–126. 
  13. Soleymani T, LoSicco K, Shapiro J. The infatuation with biotin supplementation: Is there truth
    behind its rising popularity? A comparative analysis of clinical efficacy versus social popularity. J
    Drug Dermatol. 2017:496-500.
  14. Takahashi T, Kamimura A, Yokoo Y, Honda S, Watanabe Y. The first clinical trial of topical
    application of procyanidin B-2 to investigate its potential as a hair growing agent. Phytother Res.
  15. Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair Loss A
    Systematic Review
  16. Lara Drake, BA’; Sophia Reyes-Hadsall, BS?; Jeremy Mar-tinez, BS3; et al. JAMA Dermatol.
    2023;159(1):79-86. do:10.1001/jamaderma-tol.2022.4867
  17. Klein FJ, Karim M, Li X, Adhikari S, Shapiro J, Lo Sicco K. Supplementation and hair growth: a
    retrospective chart review of patients with alopecia and laboratory abnormalities. JAAD Int.
    2022;9:69-71. do:10.1016/j.jdin.2022.08.013
  18. Ablon G, Kogan S. A Randomized, Double-Blind, Placebo-Controlled Study of a Nutraceutical
    Supplement for Promoting Hair Growth in Perimenopausal, Menopausal, and Postmenopausal
    Women With Thinning Hair. J Drugs Dermatol. 2021 Jan 1;20(1):55-61. doi: 10.36849/JDD.5701.
    PMID: 33400421.
  19. J Cosmet Dermatol. 2016 Dec;15(4):358-366. A 6-month, randomized, double-blind, placebo-
    controlled study evaluating the ability of a marine complex supplement to promote hair growth
    in men with thinning hair. Glynis Ablon. 
  20. Dermatol Res Pract. 2015;2015:841570. A 3-month, randomized, double-blind, placebo-
    controlled study evaluating the ability of an extra-strength marine protein supplement to
  21. promote hair growth and decrease shedding in women with self-perceived thinning hair. Glynis
  22. Ablon 
  23.  JAMA Dermatol. 2023 Jan 1;159(1):79-86. Evaluation of the Safety and Effectiveness of
    Nutritional Supplements for Treating Hair Loss: A Systematic Review. Lara Drake 1, Sophia
    Reyes-Hadsall 2, Jeremy Martinez 3, Christina Heinrich 1, Kathie Huang 3 4, Arash Mostaghimi 3
  24. Dietary marine-derived ingredients for stimulating hair cell cycle. Augustyniak A, Mc Mahon H.
    Biomed Pharmacother. 2023 Jul;163:114838.
  25. Hwang SB, Park HJ, Lee B-H. Hair-growth-promoting effects of the fish collagen peptide in
    human dermal papilla cells and C57BL/6 mice modulating Wnt/B-catenin and BMP signaling
    pathways. Int J Molec Sci. 2022;23:11904.
  26. M G Davis 1, J H Thomas, S van de Velde, Y Boissy, T L Dawson Jr, R Iveson, K Sutton. A novel
    cosmetic approach to treat thinning hair. Br J Dermatol. 2011 Dec;165 Suppl 3:24-30. doi:
  27. Kreider, R.B. (2003). Effects of creatine supplementation on performance and training
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  28. Van der Merwe, J., Brooks, N.E., & Myburgh, K.H. (2009). Three weeks of creatine monohydrate
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CME Information

Continuing Medical Education (CME) Credit Statement

The International Society of Hair Restoration Surgery is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. 

The International Society of Hair Restoration Surgery designates this Other Activity (blended synchronous and enduring) for a maximum of 2.00 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

To receive CME credit and a CME certificate, participants must participate in the activity, complete the evaluation survey and the CME Claim Form by January 10, 2024.


Internet/online, via computer or mobile device. 

Official Language

The official language of the webinar is English. Simultaneous interpretation is not provided for this webinar.

Disclosure Information

In accordance with the ACCME Accreditation Criteria, the ISHRS must ensure that anyone in a position to control the content of the educational activity (planners/ speakers/authors/moderators) has disclosed all financial relationships with any commercial interest (termed by the ACCME as “ineligible companies”, defined below) held in the last 24 months (see below for definitions). Please note that first authors were required to collect and submit disclosure information on behalf all other authors/contributors, if applicable.

  • Ineligible Company: The ACCME defines an “ineligible company” as any entity producing, marketing, re-selling, or distributing health care goods or services used on or consumed by patients. Providers of clinical services directly to patients are NOT included in this definition.
  • Financial Relationships: Relationships in which the individual benefits by receiving a salary, royalty, intellectual property rights, consulting fee, honoraria, ownership interest (e.g., stocks, stock options or other ownership interest, excluding diversified mutual funds), or other financial benefit. Financial benefits are usually associated with roles such as employment, management position, independent contractor (including contracted research), consulting, speaking and teaching, membership on advisory committees or review panels, board membership, and other activities from which remuneration is received, or expected.  ACCME considers relationships of the person involved in the CME activity to include financial relationships of a spouse or partner.
  • Conflict of Interest: Circumstances create a conflict of interest when an individual has an opportunity to affect CME content about products or services of an ineligible company with which he/she has a financial relationship.

The ACCME also requires that ISHRS manage any reported conflict and eliminate the potential for bias during the educational activity.  Any conflicts noted below have been managed to our satisfaction. The disclosure information is intended to identify any commercial relationships and allow learners to form their own judgments. However, if you perceive a bias during the educational activity, please report it on the evaluation.

Disclosures of Relevant Financial Relationships of Planners, Faculty, and Others

The following individuals have no relevant financial relationships with ineligible companies to disclose:


Conradin von Albertini, MD, FISHRS – Planner
Waris Anwar, MBBS, FISHRS – Planner
Victoria Ceh, MPA – Planner & Manager
Bruno F. Ferreira, MD – Planner
Steven Gabel, MD, FISHRS – Planner
James A. Harris, MD, FISHRS – Planner
Rana Irfan, MBBS, FISHRS – Planner
Sharon A. Keene, MD, FISHRS – Planner
Emily Middag – Planner and Manager
Ratchathorn Panchaprateep, MD, PhD, FISHRS – PlannerMarie A. Schambach, MD, FISHRS – Planner
Mauro Speranzini, MD, FISHRS – Faculty
Melanie Stancampiano – Planner & Manager
Mark A. Waldman, MD – Planner


Konstantinos Anastassakis, MD, PhD, FISHRS | Greece
Timothy P. Carman, MD, FISHRS | USA
Bruno Filipe Ferreira, MD | Portugal
Vikram Jayaprakash, BM, FISHRS | Australia
Sharon A. Keene, MD, FISHRS | USA
Jennifer Krejci, MD | USA
Maira Merlotto, MD, MsC | Brazil
Oscar Muñoz, MD | Spain
Nina Otberg, MD | Germany
Nicole Rogers, MD, FISHRS | USA
Bradley R. Wolf, MD, FISHRS | USA

The following individuals have relevant financial relationships:





All of the relevant financial relationships listed for these individuals have been mitigated.

Commercial Support


Off-Label Or Other Non-FDA Approved, Investigational Use

Oscar Muñoz, MD – Natural ARI inhibitors for patients seeking to avoid pharmaceuticals
Oral dutasteride, oral minoxidil

Other CME Information

Click for Continuing Medical Education Mission Statement
Learner Bill of Rights
ISHRS Privacy and Confidentiality Policy for Internet CME


The webinar content has been made available by the ISHRS for educational purposes only. The content is not intended to represent the only, nor necessarily the best, method or procedure appropriate for the medical situations discussed, but rather is intended to present views, statements, and opinions that may be of interest to others. The views expressed herein are those of the individual authors and not necessarily those of the ISHRS. The ISHRS assumes no responsibility or liability in connection with your use or misuse of the webinar content or any materials or techniques described in the content, and it makes no warranty or representation as to the validity or sufficiency of any information provided.

Questions: Learners may contact the ISHRS Headquarters with questions about this CME activity at phone +1-800-444-2737 or +1-630-262-5399, or fax +1-630-262-1520, or email: [email protected]